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If you have an M-Audio USB device that is not recognized by any applications, but is recognized in the Windows Device Manager, and has been connected to different USB ports, follow the steps below to try and resolve this issue.
Start by disconnecting your M-audio USB device
Click the Start Button, select Programs > Accessories and right-click on Command Prompt and select "Run as administrator" to launch the Command Window.
Copy and paste the following commands, one line at a time into the command window. You will need to right click in the command window to paste these commands.
Press Enter and then copy and paste the line below:
Press Enter and the Device Manager will open.
Click Show hidden devices on the View menu in Device Manager.
Right-click and choose to uninstall each instance of your M-Audio device, and if prompted to uninstall the drivers, choose yes. After all instances have been removed, restart the computer, reconnect the device and it should re-install automatically.
Try configuring your software to use your M-Audio device