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Mac OS X 10.7, 10.7.1, & 10.7.2 (Lion) Compatibility Information
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Mac OS X 10.7/10.7.1/10/7/2 (Lion) Compatibility Information – Updated March 1, 2012
Apple has now released the latest version of Mac OS X Operating System, Version 10.7 (aka Lion), the 10.7.1 update, as well as the 10.7.2 update.  This article will provide the latest compatibility information with M-Audio devices and Mac OS X 10.7 - 10.7.2. Please check for a compatible driver before installing operating system updates. Before new device drivers are released, they are tested for use with operating system versions that are available at that time. When updates for an operating system are released, all M-Audio device drivers have to be re-tested and possibly updated to ensure proper operation. We recommend not installing operating system updates until a driver has been posted for that specific operating system.

installing operating system updates, it is important to perform a complete system back, such as with Apple’s Time Machine.  It is also important to disconnect your M-Audio device before installing any Operating System update.

Please check this article for up-to-date information about device qualification.
Officially Qualified
The following devices and add-ons are qualified for use on Mac OS X 10.7 - 10.7.2 (Lion). Please visit www.m-audio.com/drivers to download the latest updates. It is only necessary to install the latest version; DO NOT install previous versions. For users that have upgraded from 10.6, please run the included uninstaller to remove previous M-Audio driver versions before installing the latest version.
Audiophile USB
Axiom Pro 25/49/61 Firmware Updater
Fast Track
Fast Track C400
Fast Track C600
Fast Track Pro
Fast Track Ultra
Fast Track Ultra 8R
Fast Track USB
FireWire Audiophile
FireWire Solo
FireWire 410
FireWire 1814
KeyStudio 49i
M-Audio Black Box
Micro USB
MobilePre MKII
MobilePre USB
Ozone USB
Producer USB
ProFire Lightbridge
ProFire 610
ProFire 2626
ProjectMix I/O
ProKeys Sono 61
ProKeys Sono 88
Pro Tools SE 8.0.3 - Patch 003 required
Pro Tools 9.0.6
Pro Tools 10
Torq 2.0.3
Transit USB
HyperControl & DirectLink Qualification

DirectLink for Ableton Live 8.2.5*
HyperControl for Ableton Live 8.2.5*
DirectLink for Cubase 5.5.3 and 6.0.5
HyperControl for Cubase 5.5.3 and 6.0.5
DirectLink for GarageBand 5
DirectLink for Logic Pro 9
HyperControl for Logic Pro 9
DirectLink for Pro Tools SE 8.0.3* - Oxygen (blue) only
HyperControl for Pro Tools SE 8.0.3*
DirectLink for Reason 5.0.1*
HyperControl for Reason 5.0.1*
DirectLink for Record 1.5.1*
HyperControl for Record 1.5.1*
* HyperControl & DirectLink are built into Ableton Live, Reason, Record, and Pro Tools SE, there are no separate personality files to install

Public Beta
The following products have updated drivers that are available as public beta to registered forum members.
Midisport 2x2 & 4x4 Anniv Ed, Midisport 8x8, 4x4, 2x2, 1x1, Uno – Please see this announcement for links and information on signing up for access to beta drivers. Please post feedback via bug reports, journal entries, or the forum on the new Centercode site. Note that you may have to click "Continue" at the bottom of the page after selecting "Audio Interface, Keyboards & MIDI Device Maintenance" in order to get to the Midisport drivers.
Pro Tools MP 9.0.5 adds public beta support for Apple's OS X Lion operating system

If you are having problems getting your device installed and recognized on Mac OS X 10.7, please make sure you are using the latest drivers posted for 10.7.1 available at www.m-audio.com/drivers, and refer to these troubleshooting guides:

If you are experiencing performance issues including crackling, dropouts, or distortion, please refer to these troubleshooting guides:
The following USB MIDI devices are class-compliant (plug & play); their drivers are part of the Mac Operating System and do not require additional drivers.  Simply connect the device to an available USB port:

Axiom 25, 49, 61*
Axiom 25, 49, 61 (2nd gen)*
Axiom Pro 25, 49, 61
eKeys 37
Keystation Pro 88
Keystation 49e, 61es, 88es
KeyStudio 25, 49
KeyRig 25, 49
Oxygen 8v2, 49, 61 (silver)**
Oxygen 25/49/61/88 (blue)**
MidAir 25/37
Midisport Uno (current model)
Midisport 1x1 (black top)
ProKeys 88, 88sx
Trigger Finger
X-Session Pro